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Curriculum Vitae

Current Employment

since Mar 2015

Application Scientist MX at Dectris Ltd, Baden, Switzerland

Previous Employment

2013-2015

X-Ray Facility Manager at Imperial College London, UK
Management of X-ray crystallography facility and Bioreactor suite
Collaborative research on structural biology projects
Safety and experimental training of facility users

2007-2013

Research Associate at Imperial College London, UK
Structural studies of regulated proteolysis and of bacterial type VI secretion
Training of postgraduate students at the bench, in lectures and tutorials
X-ray and crystallization facility management
Implementation of laboratory wiki and resource database

2005-2007

Structural Biochemist at the Institut de Biologie Structurale, Grenoble, France
Post-doctoral position supported by a Marie Curie Fellowship
Structural studies of bacterial type III secretion

1999-2004

Doctoral Student at the University of Utah, Salt Lake City, Utah, USA
Research into structure and function of proteasome–activator complexes

Qualifications

May 2005

Doctor of Philosophy in Biochemistry, University of Utah, Salt Lake City, Utah, USA
Dissertation: Mechanism of Proteasome Stimulation by 11S Activators

May 1997

Vordiplom, Friedrich-Schiller-University, Jena, Germany
Undergraduate degree in biochemistry/molecular biology

Scientific Publications

18.     EIGER detector: applications in macromolecular crystallography
A Casanas, R Warshamanage, AD Finke, E Panepucci, V Olieric, A Nöll, R Tampé, S Brandstetter, Andreas Förster, M Mueller, C Schulze-Briese, O Bunk, M Wang
Acta Cryst D (2016) 72:1036 [PDF] [suppl] [5lin] [5lio] [5lis]

17.     Dimerization of Matrix protein is required for budding of Respiratory Syncytial Virus
Andreas Förster, GN Maertens, PJ Farrell, M Bajorek
J Virol (2015) 89:4624-35 [PDF] [4d4t] [4v23]

16.     Coevolution of the ATPase ClpV, the sheath proteins TssB and TssC and the accessory protein TagJ/HsiE1 distinguishes type VI secretion classes
Andreas Förster, S Planamente, E Manoli, NS Lossi, PS Freemont, A Filloux
J Biol Chem (2014) 289:33032-43 [PDF] [4uqw] [4uqx] [4uqy] [4uqz]

15.     Structural and mechanistic insight into the Listeria monocytogenes two-enzyme lipoteichoic acid synthesis system
I Campeotto, MG Percy, JT MacDonald, Andreas Förster, PS Freemont, A Gründling
J Biol Chem (2014) 289:28054-69 [PDF] [4uop] [4uoo] [4uor]

14.     Inter-ring rotations of AAA ATPase p97 revealed by electron cryomicroscopy
HO Yeung, Andreas Förster, C Bebeacua, H Niwa, CA Ewens, C McKeown, X Zhang, PS Freemont
Open Biol (2014) 4:130142 [PDF] [suppl]

13.     Membrane and chaperone recognition by the major translocator protein PopB of the type III secretion system of Pseudomonas aeruginosa
KF Discola, Andreas Förster, F Boulay, J-P Simorre, I Attree, A Dessen, V Job
J Biol Chem (2014) 289:3591-601 [PDF] [4jl0]

12.     The HsiB1C1 (TssB/TssC) complex of the Pseudomonas aeruginosa type VI secretion system forms a bacteriophage tail sheath-like structure
NS Lossi, E Manoli, Andreas Förster, R Dajani, T Pape, PS Freemont, A Filloux
J Biol Chem (2013) 288:7536-48 [PDF] [suppl]

11.     A Salmonella kinase targets MEK to regulate the host actin cytoskeleton
C Odendall, N Rolhion, Andreas Förster, J Poh, DJ Lamont, M Liu, PS Freemont, AD Catling, DW Holden
Cell Host Microbe (2012) 12:657-68 [PDF]

10.     Distinct conformations of the p97–Ufd1–Npl4 complex revealed by electron cryomicroscopy
C Bebeacua, Andreas Förster, C McKeown, H Meyer, X Zhang, PS Freemont
Proc Natl Acad Sci USA (2012) 109:1098-103 [PDF] [suppl]

9.     Regulation of p97 in the ubiquitin–proteasome system by the UBX protein-family
P Kloppsteck, CA Ewens, Andreas Förster, X Zhang, PS Freemont
Biochim Biophys Acta (2012) 1823:125-9 [PDF]

8.     Interaction between nucleosome assembly protein 1-like family members
M Attia, Andreas Förster, C Rachez, PS Freemont, P Avner, UC Rogner
J Mol Biol (2011) 407:647-60 [PDF]

7.     Structural and functional implications of phosphorylation and acetylation in the regulation of the AAA+ protein p97
CA Ewens, P Kloppsteck, Andreas Förster, X Zhang, PS Freemont
Biochem Cell Biol (2010) 88:41-8 [PDF]

6.     AAA proteins and the life process
Andreas Förster, PS Freemont, RJ Mayer
Biochem Soc Trans (2008) 36:59-61 [PDF]

5.     The 1.9 Å structure of a proteasome–11S activator complex and implications for proteasome–PAN/PA700 interactions
Andreas Förster, EI Masters, FG Whitby, H Robinson, CP Hill
Mol Cell (2005) 18:589-99 [PDF] [suppl] [1ya7] [1yar] [1yau]

4.     Purification and analysis of recombinant 11S activators of the 20S proteasome: Trypanosoma brucei PA26 and human PA28α, PA28β, and PA28γ
EI Masters, G Pratt, Andreas Förster, CP Hill
Methods Enzymol (2005) 398:306-21 [PDF]

3.     Proteasome activators
Andreas Förster and CP Hill
in Protein Degradation, Vol. 2:  The Ubiquitin–Proteasome System by RJ Mayer, A Ciechanover, M Rechsteiner (Eds.), Wiley–VCH (2005)

2.     The pore of activated 20S proteasomes has an ordered seven-fold symmetric conformation
Andreas Förster, FG Whitby, CP Hill
EMBO J (2003) 22:4356-64 [PDF] [suppl] [1z7q]

1.     Proteasome degradation: enter the substrate
Andreas Förster and CP Hill
Trends Cell Biol (2003) 13:550-3 [PDF]

Presentations and Teaching

Andreas Förster
Introduction to X-ray Crystallography

2010 – 2014

Lecture: M.Sc. students, Imperial College London, UK

Andreas Förster, Sara Planamente, Eleni Manoli, Paul S. Freemont, and Alain Filloux
Two Type VI Secretion Classes – Implications for Sheath Disassembly

2014

Poster: 5th Murnau Conference on Structural Biology, Murnau, Germany

Professional Development

Oct 2010

Visiting Scientist with Dr. Robert E. Cohen
Colorado State University, Fort Collins, USA

Honors, Awards and Fellowships

2005–2007

Marie-Curie Postdoctoral Fellowship

2005

James W Prahl Memorial Award for Outstanding Contributions by a Graduate Student, University of Utah

1998–1999

Fulbright Scholarship

References

Letters of Reference are available from the following scientists:

Prof. Paul S. Freemont
Chair of Protein Crystallography
Imperial College London
Telephone: +44.20.7594.5327
Email: p.freemont__AT__imperial.ac.uk

Prof. Xiaodong Zhang
Professor of Macromolecular Structure and Function
Imperial College London
Telephone: +44.20.7594.3151
Email: xiaodong.zhang__AT__imperial.ac.uk

Dr. Andrea Dessen
Directeur de Recherche
Institut de Biologie Structurale
Telephone: +33.438.789590
Email: andrea.dessen__AT__ibs.fr

Prof. Christopher P. Hill
Professor of Biochemistry
University of Utah
Telephone: +1.801.585.5536
Email: chris__AT__biochem.utah.edu

Prof. Wesley I. Sundquist
Professor of Biochemistry
University of Utah
Telephone: +1.801.585.5402
Email: wes__AT__biochem.utah.edu

Current Address

DECTRIS Ltd.
Täfernhof 1
5405 Baden-Dättwil
Switzerland

Telephone: +41.56.500.2176
Telefax: +41.56.500.2176
Email: andreas.foerster__AT__dectris.com